新型磁共振成像纳米胶束型磁共振造影剂的技术

核磁共振是一种**的非侵入性临床诊断技术，但是受限于其灵敏度，针对**组织与正常组织微环境间的差异，特别是微小温度差异的检测并不能取得很好的效果。

发展了一种对生理温度范围内微小温度差异进行检测的新方法。研究者制备了一种纳米胶束型磁共振造影剂增强其灵敏度，该种造影剂能在人体生理温度范围内对微小的温度变化做出响应。利用热敏型胶束作为载体，研究者们设计了这种基于化学交换饱和转移成像的纳米磁共振造影剂。这种直径小于100纳米的胶束粒子在37度发生结构和形态的变化，改变了造影剂所携带结合水所在微环境的化学交换速率，进而使得其化学交换饱和转移效应发生了明显的改变。通过化学交换饱和转移成像方法，研究者们获得这种温度敏感型造影剂对不同温度时信号的智能放大。由于响应的温度范围接近人体生理温度，使得该造影剂在临床应用上具有重要意义。

产品供应：

影像对比剂

活体荧光造影剂

Sulfo-CY7(Cyanine7) NHSester活体荧光造影剂

Sulfo-CY7-NHS,Sulfo-Cyanine7.5NHSester,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

sulfo-CY7(Cyanine7) maleimide活体荧光造影剂

sulfo-CY7-MAL,sulfo-Cyanine7.5maleimide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) dicarboxylicacid活体荧光造影剂

Sulfo-Cyanine7.5dicarboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) carboxylicacid活体荧光造影剂

Sulfo-Cy7COOHSulfo-Cyanine7.5carboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) azide活体荧光造影剂

Sulfo-CY7/N3,Sulfo-Cyanine7.5azide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) alkyne活体荧光造影剂

Sulfo-CY7-alkyne,Sulfo-Cyanine7.5alkyne,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) tetrazine活体荧光造影剂

Sulfo-Cyanine7tetrazine,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) NHSester活体荧光造影剂

Sulfo-Cyanine7NHSester,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) maleimide活体荧光造影剂

Sulfo-Cyanine7maleimide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

sulfo-CY7(Cyanine7) dicarboxylicacid活体荧光造影剂

sulfo-Cyanine7dicarboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) carboxylicacid活体荧光造影剂

Sulfo-Cyanine7carboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) bis-NHSester活体荧光造影剂

Sulfo-Cyanine7bis-NHSester,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) azide活体荧光造影剂

Sulfo-Cyanine7azide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) amine活体荧光造影剂

Sulfo-Cyanine7amine,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) alkyne活体荧光造影剂

Sulfo-Cyanine7alkyne,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) tetrazine活体荧光造影剂

Cyanine7.5tetrazine,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) NHSester活体荧光造影剂

Cyanine7.5NHSester,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) maleimide活体荧光造影剂

Cyanine7.5maleimide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) hydrazide活体荧光造影剂

Cyanine7.5hydrazide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) carboxylicacid活体荧光造影剂

Cyanine7.5carboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7 (Cyanine7) azide活体荧光造影剂

Cyanine7.5azide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7 (Cyanine7) azide,10mM/DMSO活体荧光造影剂

Cyanine7.5azide,10mM/DMSO,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) amine活体荧光造影剂

Cyanine7.5amine,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) alkyne活体荧光造影剂

Cyanine7.5alkyne,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) tetrazine活体荧光造影剂

Cyanine7tetrazine,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) NHSester活体荧光造影剂

Cyanine7NHSester,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) maleimide活体荧光造影剂

Cyanine7maleimide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) hydrazide活体荧光造影剂

Cyanine7hydrazide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) dicarboxylicacid活体荧光造影剂

Cyanine7dicarboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) DBCO活体荧光造影剂

Cyanine7DBCO,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) carboxylicacid活体荧光造影剂

Cyanine7carboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) azide活体荧光造影剂

Cyanine7azide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) azide,10mM/DMSO活体荧光造影剂

Cyanine7azide,10mM/DMSO,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) amine活体荧光造影剂

Cyanine7amine,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) alkyne活体荧光造影剂

Cyanine7alkyne,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

BDP650/665XNHSester活体荧光造影剂

BDP650/665XNHSester,Borondipyrromethenedyeforfluorescein(516nm)channel-verybrightandphotostablefluorophore.

BDP650/665maleimide活体荧光造影剂

BDP650/665maleimide,Borondipyrromethenedyeforfluorescein(515nm)channel-verybrightandphotostablefluorophore.

BDP650/665azide活体荧光造影剂

BDP650/665azide,Borondipyrromethenedyeforfluorescein(514nm)channel-verybrightandphotostablefluorophore.

BDP650/665alkyne活体荧光造影剂

BDP650/665alkyne,Borondipyrromethenedyeforfluorescein(513nm)channel-verybrightandphotostablefluorophore.

BDP630/650XNHSester活体荧光造影剂

BDP630/650XNHSester,Borondipyrromethenedyeforfluorescein(512nm)channel-verybrightandphotostablefluorophore.

BDP630/650tetrazine活体荧光造影剂

BDP630/650tetrazine,Borondipyrromethenedyeforfluorescein(511nm)channel-verybrightandphotostablefluorophore.

BDP630/650maleimide活体荧光造影剂

BDP630/650maleimide,Borondipyrromethenedyeforfluorescein(510nm)channel-verybrightandphotostablefluorophore.

BDP630/650hydrazide活体荧光造影剂

BDP630/650hydrazide,Borondipyrromethenedyeforfluorescein(509nm)channel-verybrightandphotostablefluorophore.

BDP630/650carboxylicacid活体荧光造影剂

BDP630/650carboxylicacid,Borondipyrromethenedyeforfluorescein(508nm)channel-verybrightandphotostablefluorophore.

BDP630/650azide活体荧光造影剂

BDP630/650azide,Borondipyrromethenedyeforfluorescein(507nm)channel-verybrightandphotostablefluorophore.

BDP630/650amine活体荧光造影剂

BDP630/650amine,Borondipyrromethenedyeforfluorescein(506nm)channel-verybrightandphotostablefluorophore.

BDP630/650alkyne活体荧光造影剂

BDP630/650alkyne,Borondipyrromethenedyeforfluorescein(505nm)channel-verybrightandphotostablefluorophore.

T2型造影剂-超顺磁性四氧化三铁颗粒（USPIO/SPIO）

T2对比剂（顺磁性铁锰）

普鲁士蓝纳米颗粒

普鲁士蓝纳米颗粒；纯水溶液；粒径：100nm

亲和素表面磁性氧化铁微球（1um）

1um亲和素包裹的磁性四氧化三铁微球；纯水溶液；粒径：1±0.1um

羧基表面磁性氧化铁微球（1um）

1um羧基化磁微球；纯水溶液；粒径：1±0.1um

磁性氧化铁纳米球（500nm）

500nm磁性氧化铁纳米球；纯水溶液；粒径：300±50nm

磁性氧化铁纳米球（300nm）

300nm磁性氧化铁纳米球；纯水溶液；粒径：300±50nm

磁性氧化铁纳米球（200nm）

200nm磁性氧化铁纳米球；纯水溶液；粒径：200±50nm

PEG化磁性锰锌铁氧体纳米晶（氨基）

PEG化磁性锰锌铁氧体纳米晶（-NH2）；纯水溶液；粒径：10±5nm

PEG化磁性锰锌铁氧体纳米晶（羧基）

PEG化磁性锰锌铁氧体纳米晶（-COOH）；纯水溶液；粒径：10±5nm

PEG化磁性锰锌铁氧体纳米晶（甲氧基）

PEG化磁性锰锌铁氧体纳米晶（-OCH3）；纯水溶液；粒径：10±5nm

锰锌铁氧体纳米晶

锰锌铁氧体纳米晶（高温热解法）；氯仿溶液；粒径：25±5nm

荧光素标记Fe3O4颗粒;USPIO;SA-DSPE-PEG-Fe3O4

荧光素修饰的四氧化三铁磁性纳米颗粒（FITC-Fe3O4）；纯水溶液；粒径：10±5nm

亲和素表面Fe3O4颗粒SA-DSPE-PEG-Fe3O4;10nm

链霉亲和素修饰的四氧化三铁磁性纳米颗粒（SA-Fe3O4）；纯水溶液；粒径：10±5nm

氨基端PEG化Fe3O4颗粒;DSPE-PEG-Fe3O4（-NH2）;10nm

PEG化四氧化三铁磁性纳米颗粒（-NH2）；纯水溶液；粒径：10±5nm

羧基端PEG化Fe3O4颗粒;DSPE-PEG-Fe3O4（-COOH）;10nm

PEG化四氧化三铁磁性纳米颗粒（-COOH）；纯水溶液；粒径：10±5nm

甲氧基PEG化Fe3O4颗粒;DSPE-PEG-Fe3O4（-CH3O）；50nm

PEG化四氧化三铁磁性纳米颗粒（-OCH3）；氯仿溶液；粒径：50±5nm

PEG化Fe3O4颗粒;25nm;PEG-Fe3O4

PEG化四氧化三铁磁性纳米颗粒（-OCH3）；纯水溶液；粒径：25±5nm

PEG化Fe3O4颗粒;PEG-USPIO；10nm

PEG化四氧化三铁磁性纳米颗粒（-OCH3）；纯水溶液；粒径：10±5nm

油酸表面Fe3O4颗粒氯仿溶液;OA-Fe3O4-C

油酸修饰的四氧化三铁磁性纳米颗粒（OA-Fe3O4，高温热解法）；氯仿溶液；粒径：10±5nm

油酸表面Fe3O4颗粒粉末;OA-USPIO

油酸修饰的四氧化三铁磁性纳米颗粒（OA-Fe3O4，高温热解法）；固体粉末；粒径：10±5nm

磁性石墨烯;MagneticGR

磁性石墨烯溶液（500mg）

载USPIO聚苯乙烯纳米粒

磁性聚苯乙烯纳米球（PS-Fe3O4）；纯水溶液；粒径：100±50nm

二氧化硅表面Fe3O4颗粒;SiO2-Fe3O4

二氧化硅修饰的四氧化三铁磁性纳米颗粒（SiO2-Fe3O4）；纯水溶液；粒径：10±5nm

羧基表面Fe3O4颗粒;DMSA-USPIO

羧基化四氧化三铁磁性纳米颗粒（DMSA-Fe3O4）；纯水溶液；粒径：10±5nm

PEI氨基表面Fe3O4颗粒;PEI-USPIO

聚乙烯亚胺修饰的四氧化三铁磁性纳米颗粒（PEI-Fe3O4）；纯水溶液；粒径：10±5nm

油酸表面Fe3O4颗粒;OA-USPIO

油酸修饰的四氧化三铁磁性纳米颗粒（OA-Fe3O4，共沉淀法）；纯水溶液；粒径：10±5nm

氨基表面Fe2O3颗粒；APTS-Fe2O3

氨基化三氧化二铁磁性纳米颗粒（APTS-Fe2O3）；纯水溶液；粒径：10±5nm

羧基表面Fe2O3颗粒；DMSA-Fe2O3

羧基化三氧化二铁磁性纳米颗粒（DMSA-Fe2O3)；纯水溶液；粒径：10±5nm

PLL修饰Fe2O3颗粒

PLL-Fe2O3多聚赖氨酸修饰的三氧化二铁磁性纳米颗粒（PLL-Fe2O3）；纯水溶液；粒径：10±5nm

γ-Fe2O3

伽马-三氧化二铁磁性纳米颗粒（γ-Fe2O3）；纯水溶液；粒径：10±5nm

上述产品齐岳生物均可供应，仅用于科研！

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