产品名称：

4-amino-1,8-Naphthalimide，1742-95-6，6-amino-1H-benz[de]isoquinoline-1,3(2H)-dione

产地：西安

规格：1mg 5mg 10mg

纯度：99%

用途：仅用于科研

温馨提示：仅用于科研，不能用于人体实验！

The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species.1,2 4-amino-1,8-Naphthalimide (4-ANI) is an inhibitor of PARP (IC50 = 180 nM).3 It blocks radiation-induced PARP in cancer cells, potentiating the cytotoxicity of γ-radiation, although it is not cytotoxic in the absence of radiation.4 4-ANI is used to study the role of PARP activity in various cell systems.

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编辑：XAQYBIO HAO，2023年3月15日。