产品名称：

OBA-09，856095-68-6，2-(1,2-dioxopropoxy)-benzoic acid

产地：西安

规格：1mg 5mg 10mg

纯度：99%

用途：仅用于科研

温馨提示：仅用于科研，不能用于人体实验！

OBA-09 is an ester of pyruvate and salicylic acid that has neuroprotective properties.1 It decreases lactate dehydrogenase (LDH) release and prevents cell death induced by NMDA or zinc, and reduces the production of reactive oxygen species (ROS) induced by oxygen-glucose deprivation in mixed rat primary cortical cells when used at concentrations of 10 and 15 mM. OBA-09 (10 mg/kg) reduces infarct volume by 89.9% and decreases expression of IL-1β, inducible nitric oxide synthase (iNOS), COX-2, and TNF-α in the brain in a rat model of ischemia induced by middle cerebral artery occlusion (MCAO).1,2 It improves motor performance in the rotarod test in the same model when administered at a dose of 10 mg/kg.1

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编辑：XAQYBIO HAO，2023年3月15日。