DBCO试剂可用于标记叠氮化物修饰的生物分子

产品名称：DBCO-PEG-SH DBCO-PEG-Thiol

中文名称：二苯并环辛炔-聚乙二醇-巯基

PEG分子量：1k，2k，3.4k，5k，10k其他分子量可定制

存储条件：≤-4℃低温干燥保存

产品外观: 固体或黏稠液体，取决于分子量

常用溶剂：溶于大部分有机溶剂，如：DCM、DMF、DMSO、THF等等。在水中有很好的溶解性

DBCO（二苯并环辛炔）聚乙二醇硫醇（DBCO-PEG-SH）衍生物无需任何金属催化剂即可进行化学反应。菌株促进的环辛炔和叠氮化合物的1,3-偶*环加成反应，也称为无铜点击反应，是一种生物正交反应，可使两个分子在水溶液中共轭。DBCO-PEG衍生物在水相缓冲液中具有快速动力学和稳定性。DBCO试剂可用于标记叠氮化物修饰的生物分子，而不需要有毒的铜催化剂。聚乙二醇化可以增加肽和蛋白质的溶解性和稳定性，并降低其免疫原性。它还可以抑制带电分子与修饰表面的非特异性结合。

DBCO (dibenzocyclic octyne) polyethylene glycol mercaptan (DBCO-PEG-SH) derivatives can conduct chemical reactions without any metal catalyst. The 1,3-dipolar cycloaddition reaction of cyclooctyne and azide compounds promoted by the strain, also known as copper free click reaction, is a bioorthogonal reaction, which can make two molecules conjugate in aqueous solution. DBCO-PEG derivatives have fast kinetics and stability in aqueous buffer solution. DBCO reagent can be used to label azide modified biomolecules without toxic copper catalyst. Polyethylene glycol can increase the solubility and stability of peptides and proteins, and reduce their immunogenicity. It can also inhibit the nonspecific binding of charged molecules to the modified surface.

相关产品：

DBCO-PEG1K-FITC

DBCO-PEG2K-FITC

DBCO-PEG3.4K-FITC

DBCO-PEG-5K-FITC

DBCO-PEG10K-FITC

DBCO-MPEG1K

DBCO-MPEG2K

DBCO-MPEG3.4K

DBCO-MPEG5K

DBCO-MPEG10K

DBCO-PEG1K-MAL

DBCO-PEG2K-MAL

DBCO-PEG3.4K-MAL

DBCO-PEG5K-MAL

DBCO-PEG10K-MAL

用途:科研

纯度:≥95%

保存时间: 1年

产地:西安

供应商：西安齐岳创科生物科技有限公司

注意事项:仅用于科研不用于人体