RGD修饰的海藻酸钠，Sodium alginate；DSPE-PCB20两性甜菜碱聚合物胶束聚合度/RGD修饰的海藻酸钠；DSPE-PCB 两性甜菜碱聚合物胶束

使用两性甜菜碱聚合物胶束(DSPE-PCB)来模拟衣壳病毒的表面特征(图1a)，并封装模型蛋白。聚羧酸甜莱碱(PCB)通过质子辅助氨基酸转运蛋白1(PAT1)穿透上皮细胞层(图1b)。PAT1可以促进甜菜碱和甜菜碱衍生物渗透到上皮细胞层。

Because of the sharp contrast in polarity between the superhydrophilic tail and the superhydrophobic head of DSPE–PCB 5K, its micelles stabilize docetaxel at extremely dilute conditions, at which conventional micelles dissociate. In vivo, the ultrastability of the formulation enables a larger amount of drug to reach the tumour through the enhanced permeability and retention effect. Chemical structure reproduced from ref. 8, Macmillan Publishers Ltd.

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仅用于用于科研，不能用于人体试验（zyl 2022.04.11)