中文名 异鼠李素

英文名 isorhamnetin

中文别名 3,5,7-三羟基-2-(4-羟基-3-甲氧基苯基)苯并吡喃-4-酮

密度 1.6±0.1 g/cm3

沸点 599.4±50.0 °C at 760 mmHg

熔点 307°C

分子式 C16H12O7

分子量 316.262

闪点 227.8±23.6 °C

精确质量 316.058289

PSA 120.36000

LogP 1.76

外观性状 固体;Light yellow to Amber to Dark green powder to crystal

蒸汽压 0.0±1.8 mmHg at 25°C

折射率 1.741

储存条件 密封储存，储存于阴凉、干燥的库房。

稳定性 常温常压下稳定，避免与强氧化剂接触。

"Isorhamnetin on experimental IBD via PXR-mediated up-regulation of xenobiotic metabolism and down-regulation of NF-κB signaling.

Isorhamnetin is efficacious in protecting hepatocytes against oxidative stress by Nrf2 activation and in inducing the expressions of its downstream genes.

Isorhamnetin may contribute to blockade of the host-destructive processes mediated by IL-6 and could be a highly efficient modulator of the host response in the treatment of inflammatory periodontal disease. 

Isorhamnetin has anti-tumor activity, has cytotoxic effect on BEL-7402 cells  with IC50 equal to 74.4±1.13 ug/ml after treatment with isorhamnetin for 72 h. 

Isorhamnetin and quercetin prevent angiotensin II (AngII)-induced endothelial dysfunction by inhibiting the overexpression of p47(phox) and the subsequent increases O2-production, resulting in increased nitric oxide bioavailability.

Isorhamnetin, kaempferol, and quercetin preferentially inhibit the in vitro catalytic activity of human CYP1B1.

Isorhamnetin has anti-adipogenic effects in mouse 3T3-L1 cells, it inhibits the adipogenic differentiation of hAMSCs and that its mechanisms are mediated by the stabilization of β-catenin.

8. Isorhamnetin inhibits the H(2)O(2)-induced activation of the intrinsic apoptotic pathway via ROS scavenging and ERK inactivation, thus, it is a promising reagent for the treatment of ROS-induced cardiomyopathy."

包装：100mg，500mg，1g，10g，100g以及kg级别等公斤级大包装

纯度：99%

配送：惯例下常温**

包装：袋装

厂家：西安齐岳生物科技有限公司

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西安齐岳生物科技有限公司具备批量生产能力和强大的研发能力，这样的双重优势可以确保企业不仅在满足市场需求上保持高效，同时也在产品创新和技术升级。能够提供100mg，500mg，1g，10g，100g以及kg级别等公斤级大包装。

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