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CAS:472-11-7 Ruscogenin 鲁斯可皂苷元
发布时间:2024-04-01     作者:kx   分享到:

中文名 鲁斯可皂苷元

英文名 Ruscogenin

中文别名 鲁斯考皂苷元 | 鲁斯皂苷元 | 螺可吉宁

密度 1.2±0.1 g/cm3

沸点 563.1±50.0 °C at 760 mmHg

熔点 198-202ºC

分子式 C27H42O4

分子量 430.62

闪点 294.4±30.1 °C

精确质量 430.308319

PSA 58.92000

LogP 4.29

蒸汽压 0.0±3.5 mmHg at 25°C

折射率 1.577

储存条件 2~8℃

"Ruscogenin has been found to exert significant anti-inflammatory and anti-thrombotic activities; the possible mechanism of the anti-inflammatory activity  is role of intercellular adhesion molecule-1 and nuclear factor-kappaB. 

 Ruscogenin significantly attenuates LPS-induced acute lung injury (ALI )via inhibiting expressions of TF and iNOS and NF-κB p65 activation, indicates that it as a potential therapeutic agent for ALI or sepsis. 

 Ruscogenin can protect the brain against ischemic damage caused by  middle cerebral artery occlusion (MCAO), and this effect may be through downregulation of NF-κB-mediated inflammatory responses. 

 Ruscogenin inhibits activation of neutrophil through cPLA 2 , PAK, Akt, MAPKs, cAMP, and PKA signaling pathways. 

 Ruscogenin may attenuate high-fat diet (HFD)-induced steatohepatitis through downregulation of NF- κB-mediated inflammatory responses, reducing hepatic lipogenic 

gene expression, and upregulating proteins in β-oxidation pathway."

CAS:472-11-7  Ruscogenin    鲁斯可皂苷元

包装:100mg,500mg,1g,10g,100g以及kg级别等公斤级大包装

纯度:99%

配送:惯例下常温**

包装:袋装

厂家:西安齐岳生物科技有限公司

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