中文名 阿莫曲坦

英文名 almotriptan malate

中文别名 依来曲普坦 | 马来酸阿莫曲普坦 | 苹果酸阿莫曲坦

密度 1.27g/cm3

沸点 538.7ºC at 760mmHg

熔点 170-172ºC

分子式 C21H31N3O7S

分子量 469.552

闪点 279.6ºC

精确质量 469.188263

PSA 159.62000

LogP 2.12290

外观性状 淡黄色固体

蒸汽压 1.13E-11mmHg at 25°C

储存条件 -20°C Freezer

水溶解性 水溶性：可溶

"Almotriptan Malate is a 5-HT1B/1D-receptor agonist used to treat migraine.

IC50:

Target: 5-hydroxytryptamine1B/1D (5-HT1B/1D) Receptor

Almotriptan Malate is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults. Almotriptan showed low nanomolar affinity for the 5-HT(1B) and 5-HT(1D) receptors in several species, including the human, while affinity for 5-HT receptors other than 5-HT(1B/1D) was clearly less. Almotriptan did not exhibit significant affinity for several non-5-HT receptors studied up to 100 microM. Almotriptan inhibited forskolin-stimulated cyclic AMP accumulation in HeLa cells transfected with 5-HT(1B) or 5-HT(1D) human receptors . Almotriptan had a mild antiemetic effect and a slight, transient diuretic effect in dogs, although the latter effect is probably of no clinical relevance. In addition, no effect on the respiratory system of conscious guinea pigs was observed following almotriptan treatment. These results indicate that almotriptan has a favourable safety profile with respect to the central nervous, renal and respiratory systems ."

包装：100mg，500mg，1g，10g，100g以及kg级别等公斤级大包装

纯度：99%

配送：惯例下常温**

包装：袋装

厂家：西安齐岳生物科技有限公司

关于我们：

西安齐岳生物科技有限公司具备批量生产能力和强大的研发能力，这样的双重优势可以确保企业不仅在满足市场需求上保持高效，同时也在产品创新和技术升级。能够提供100mg，500mg，1g，10g，100g以及kg级别等公斤级大包装。

相关产品：

CAS:112-80-1 Oleic acid

CAS:143-19-1 Sodium oleate

CAS:516-35-8 Taurochenodeoxycholic acid

CAS:17659-49-3 Racanisodamine

CAS:5610-40-2 (-)-Securinine

CAS:75921-69-6 Melanotan I