中文名 泼尼松龙磷酸钠
英文名 Prednisolone phosphate sodium
中文别名 泼尼松龙21-磷酸二钠 | 3-氨基-1-羟基丙亚基-1,1-二磷酸二钠
沸点 100 °C
分子式 C21H27Na2O8P
分子量 484.388
闪点 361.9ºC
精确质量 484.123901
PSA 156.83000
LogP 2.55100
蒸汽压 4.17E-21mmHg at 25°C
储存条件 室温
"Prednisolone disodium phosphate is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
Target: Glucocorticoid Receptor
Prednisolone irreversibly binds with glucocorticoid receptors (GR) alpha and beta for which they have a high affinity. Prednisolone can activate and influence biochemical behaviour of most cells. The steroid/receptor complexes dimerise and interact with cellular DNA in the nucleus, binding to steroid-response elements and modifying gene transcription. They induce synthesis of some proteins, and inhibit synthesis of others. Prednisolone exerted a delayed biphasic effect on the resistant CCRF-CEM leukemic cell line, necrotic at low doses and apoptotic at higher doses. At low doses, prednisolone exerted a pre-dominant mitogenic effect despite its induction on total cell death, while at higher doses, prednisolone's mitogenic and cell death effects were counterbalanced ."
包装:100mg,500mg,1g,10g,100g以及kg级别等公斤级大包装
纯度:99%
配送:惯例下常温**
包装:袋装
厂家:西安齐岳生物科技有限公司
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