中文名 三氟柳

英文名 2-acetyloxy-4-(trifluoromethyl)benzoic acid

中文别名 三氟醋铆酸 | 2-乙酰氧基-4-三氟甲基苯甲酸 | 三氟醋柳酸 | 卡巴他塞

密度 1.4±0.1 g/cm3

沸点 316.0±42.0 °C at 760 mmHg

熔点 115 °C

分子式 C10H7F3O4

分子量 248.155

闪点 144.9±27.9 °C

精确质量 248.029648

PSA 63.60000

LogP 2.90

外观性状 固体;White to Almost white powder to crystal

蒸汽压 0.0±0.7 mmHg at 25°C

折射率 1.484

储存条件 2-8°C

水溶解性 水溶性：不溶

"Triflusal irreversibly inhibits the production of thromboxane-B2 in platelets by acetylating cycloxygenase-1.

Target: COX

Triflusal at 10 mM, 100 mM and 1 M decreases LDH efflux in rat brain slices after anoxia/reoxygenation by 24%, 35% and 49% respectively. Triflusal also reduces inducible NO synthase activity by 18%, 21% and 30% [1].

Triflusal (10 mg/kg i.v.) reduces platelet deposition on subendothelium-induced primary thrombus by about 68% in rabbits. Triflusal (10 mg/kg i.v.) reduces platelet deposition on a fresh thrombus formed over tunica media by about 48% in rabbits. Triflusal (40 mg/kg p.o.) reduces platelet deposition on a primary thrombus triggered by subendothelium and tunica media by 53% in rabbits. Triflusal (40 mg/kg p.o.) significantly reduces Cox-2 mRNA levels and protein levels without influence Cox-1 mRNA levels on the vascular wall in rabbits [2]. Triflusal (600 mg/day for 5 days) results in an increase in NO production by neutrophils and an increase in endothelial nitric oxide synthase (eNOS) protein expression in neutrophils in healthy volunteers [3]."

包装：100mg，500mg，1g，10g，100g以及kg级别等公斤级大包装

纯度：99%

配送：惯例下常温**

包装：袋装

厂家：西安齐岳生物科技有限公司

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