文献：肽-PEG-脂质复合物的合成方法：奥曲肽-PEG-DSPE合成的应用

链接：https://www.sciencedirect.com/science/article/abs/pii/S0960894X08007944

作者：苏建秋  ，曾锦 禄 ，张定光  ，余文仁  ，吴世光 

节选：

建立了一种肽-聚乙二醇-脂质（肽-PEG-脂质）偶联物的固相合成方法。以奥曲肽-PEG 2000 -DSPE（OPD 2000）为例，演示了该合成方法。所得OPD 2000的结构、活性和纯度均已确认，为制备靶向脂质体等结构明确的药物递送系统提供了靶向分子，以供进一步研究。

A solid phase synthesis method was established for the synthesis of peptide-poly(ethylene glycol)-lipid (peptide-PEG-lipid) conjugates. Octreotide-PEG2000-DSPE (OPD2000) was used as an example to demonstrate the synthetic approach. The OPD2000 obtained had confirmed structure, activity, and purity providing a targeting molecule for preparation of well-defined drug delivery systems, such as targeted liposomes, for further studies.

西安齐岳生物提供相关产品：

DSPE-PEG-Boronate

mPEG-DMPE

EB1-PEG-DSPE

DSPE-PEG-HZ

DSPE-PEG-PEI

DSPE-PEG-c(RGDfc)

DMPE (14:0 PE)

DSPE-PEG-scFv(HD37-CCH)（二硬脂酰基磷脂酰乙醇胺-聚乙二醇-肿瘤靶向蛋白)

以上文章内容来源各类期刊或文献，如有侵权请联系我们删除！