产品名称：

Plumbagin，481-42-5，5-hydroxy-2-methyl-1,4-naphthalenedione

产地：西安

规格：1mg 5mg 10mg

纯度：99%

用途：仅用于科研

温馨提示：仅用于科研，不能用于人体实验！

Plumbagin is a natural 1,4-naphthoquinone first isolated from plants of the genus Plumbago. It has diverse effects in cells and animals. Plumbagin causes the generation of reactive oxygen species and induces apoptosis in cancer cells.1,2 It activates signaling through Nrf2 and the antioxidant response element, inducing the expression of Nrf2 target genes, including NQO1 and heme oxygenase-1 in cultured neuronal cells.1 Plumbagin also inhibits NADPH oxidase 4 in a time- and dose-dependent manner.3 It can be protective against peroxide stress or deprivation of glucose or oxygen.

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编辑：XAQYBIO HAO，2023年3月15日。